BackDuration: 15 minutes
Aids in the diagnosis and management of thyroid gland disorders
Clinical significance of test
Thyroid stimulating hormone (TSH) is produced by the pituitary gland in your brain. This gland tells your thyroid to make and release the thyroid hormones into your blood. TSH is made in a gland in the brain called the pituitary. When thyroid levels in your body are low, the pituitary gland makes more TSH. When thyroid levels are high, the pituitary gland makes less TSH. TSH levels that are too high or too low can indicate your thyroid isn’t working correctly. Your thyroid makes hormones that regulate the way your body uses energy. It also plays an important role in regulating your weight, body temperature, muscle strength, and even your mood.
Steps of operation
Clinical application
TSH increase:
- Serum TSH is significantly elevated in patients with hypothyroidism. In patients with primary hypothyroidism receiving thyroid hormone replacement therapy, serum TSH is also an important follow-up indicator for efficacy evaluation.
- The increase of serum TSH can be seen in patients with chronic lymphocytic thyroiditis, endemic goiter, pituitary secreting thyroid stimulating hormone adenoma and excessive use of thyroid hormone.
TSH decrease:
- TSH is decreased in hyperthyroidism. The determination of TSH is an important and sensitive index in the diagnosis of hyperthyroidism.
- It may be acromegaly, Cushing’s syndrome, dopamine and glucocorticoid.
Interpretation of results
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