BackDuration: 15 minutes
A neurobiochemical marker, indicative of brain injury, tumours and other neurodegenerative conditions
Clinical significance of test
Serum Protein S100β (S100β) is a calcium-binding protein that is found in astrocyte cells of the central nervous system. Its levels in biological fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are recognized as a reliable biomarker of active neural distress. When it is released at high concentration, through its Receptor for Advanced Glycation Endproducts, it triggers tissue reaction to damage in a series of different neural disorders.
Steps of operation
Clinical application
- Used in monitoring patients with malignant melanoma (used with combination of clinical and histological features)
- Biochemical marker of Traumatic Brain Injury (TBI), also as a surrogate marker for TBI treatment efficacy
Interpretation of results
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